Vol 1, Issue 1 (2017)

Published on 2017-12-27

Effects of 6-substituted-2-oxo-1,2-dihydroquinoline-4-carboxylic acid derivatives on mild steel corrosion in hydrochloric acid solution: Experimental and theoretical studies, and their antibacterial activity

Abstract:

The corrosion inhibitory effect of two 2-oxo-1,2-dihydroquinoline-4-carboxylic acid derivatives, namely 6-bromo-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (P1) and 6-chloro-2-oxo-1,2-dihydroquinoline-4-carboxylic acid (P2) for mild steel in 1M HCl has been studied using electrochemical impedance spectroscopy (EIS), Tafel polarization curves and weight loss measurements. It was found that the inhibition efficiency of the two investigated inhibitors increases with increase in concentration of inhibitors. P1 and P2 show corrosion inhibition efficiency of 90 and 92%, respectively at 10−3M and 308 K. Impedance experimental data revealed a frequency distribution of the capacitance, simulated as constant phase element. Potentiostatic polarization study showed that P1 and P2 are mixed-type inhibitors in 1M HCl. The results obtained from electrochemical and weight loss studies were in reasonable agreement. The adsorption of P1 and P2 on steel surface obeys Langmuir's adsorption isotherm. The correlation between inhibition efficiency and molecular structure of the inhibitors is investigated by determination of chemical indexes, which were performed using density functional theory (DFT) at (B3LYP/6-31G) (d,p) level. Finally the antibacterial activity evaluation of both products showed their strong antibacterial activity against several tested bacterial strains. So, products P1 and P2 can serve as basic compounds in the synthesis of active drugs against bacterial infections due to sensitive gram (+) and Gram (-)bacteria.

Authors:

  • Yassir Filali Baba
  • Nada Kheira Sebbar
  • Hicham Elmsellem
  • Youssef Kandri Rodi
  • Marwa Chraibi
  • Kawtar Fikri Benbrahim
  • Fouad Ouazzani Chahdi
  • El Mokhtar Essassi
  • Maria Plamenova Nikolova
  • Hanae Steli

Keywords:

  • Quinoline
  • Mild steel
  • Polarization
  • Electrochemical impedance spectroscopy
  • Quantum chemical calculations (DFT)

Pages: 11

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