Vol 2, Issue 1 (2018)
Published on 2018-02-28
Stoichiometric and theoritical study of the alkylation reaction of 5-nitro-1H-benzo [d] imidazol-2 (3H)-one
Abstract:
In this paper, we report the synthesis of new heterocycl containing the benzimidazole nucleus. Imidazol nitrogen was alkyled using potassium carbonat as the base with the presence of a catalytic quantity of tetra-n-butylammonium bromide under mild condition. The structures of these products were determined using 1H NMR, 13C NMR and MS, the crystalline structure of some compounds obtained from X-ray diffraction confirms our proposed structures.
Authors:
- Younes Ouzidan
- Youssef Kandri Rodi
- Nada Kheira Sebbar
- Hicham Elmsellem
- Fouad Ouazzani Chahdi
- El Mokhtar Essassi
Keywords:
- Benzimidazole
- X-Ray
- Alkylation
- DFT
Pages: 6