Vol 2, Issue 3 (2018)

Published on 2018-10-30

Abstract:

Pyrazole derivatives containing a benzimidazole skeleton exhibit a wide range of important pharmacological activities, the most relevant one being their anti-cancer activity. For this reason, we performed a predictive quantitative structure activity relationships (QSAR) analysis of the anti-cancer activity against three human tumor cell lines using a statistical approach: lung A549, breast MCF-7 and cervical Hela.

Authors:

  • Khalid Dguigui
  • Menana El Hallaoui
  • Nidal Naceiri Mrabti

Key words:

  • QSAR
  • Tumor cells lines
  • Pyrazole derivative
  • Anticancer

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